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Current status and challenges for cell-cultured milk technology: a systematic review
Hyuk Cheol Kwon1, Hyun Su Jung1, Vahinika Kothuri1
1Department of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul, Republic of Korea.
Journal of Animal Science and Biotechnology
|June 7, 2024
Summary
Cellular agriculture offers sustainable dairy alternatives. This review explores animal cell-based milk production, focusing on mammary epithelial cells and technical challenges for industry innovation.
Area of Science:
- Agricultural Science
- Biotechnology
- Food Science
Background:
- Cellular agriculture provides sustainable alternatives to traditional farming.
- The dairy sector is increasingly exploring cellular agriculture for milk production.
- Current methods include precision fermentation and animal cell culture.
Purpose of the Study:
- To review the current state of cellular agriculture in the dairy sector.
- To identify technical challenges in cell-cultured milk production.
- To explore animal cell-based approaches for dairy components.
Main Methods:
- Review of existing literature on cellular agriculture in dairy.
- Classification of dairy cellular agriculture into fermentation-based and animal cell culture-based methods.
- Focus on the structural, functional, and productive aspects of mammary epithelial cells.
Main Results:
- Precision fermentation is used by companies to synthesize milk components.
- Animal cell-based technology is emerging due to concerns about GMOs in precision fermentation.
- Mammary epithelial cells are key to understanding cell-cultured milk production.
Conclusions:
- Cellular agriculture presents viable alternatives for dairy production.
- Animal cell-based technology requires further research into mammary epithelial cell biology.
- Addressing technical challenges is crucial for advancing cell-cultured milk.
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