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Recipient-Donor Sex Combinations and Posttransplant Infections: A Swiss Transplant Cohort Study.

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Donor-derived infections: The Swiss perspective.

Nicolas J Mueller1, Oriol Manuel2, Cédric Hirzel3

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Switzerland

Keywords:
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Area of Science:

  • Transplant infectious diseases
  • Organ transplantation epidemiology

Background:

  • Switzerland lacks a systematic approach to donor-derived infections.
  • Small country size and close collaboration aid rapid communication.
  • Transplant infectious disease teams work closely together.

Purpose of the Study:

  • To describe the current approach to managing suspected donor-derived infections in Switzerland.
  • To highlight the role of the Swiss Transplant Cohort Study in detecting such infections.

Main Methods:

  • Intensive collaboration between transplant infectious disease teams.
  • Rapid information sharing on suspected donor infections.
  • Long-term observational Swiss Transplant Cohort Study (STCS) data collection.
  • STCS includes >92% of solid organ recipients.

Main Results:

  • Rapid communication facilitates prompt discussion and measures for suspected donor infections.
  • The STCS effectively collects infectious disease episodes.
  • The STCS aids in detecting patterns of potential donor-derived infections.

Conclusions:

  • Despite no systematic approach, Switzerland's structure enables swift management of donor-derived infections.
  • The STCS is a valuable tool for identifying and analyzing donor-derived infections in solid organ transplantation.