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Related Experiment Videos

Familiar hyperkalaemic acidosis.

J H Licht, D Amundson, W A Hsueh

    The Quarterly Journal of Medicine
    |February 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Type II pseudohypoaldosteronism causes acidosis due to enhanced chloride reabsorption, not mineralocorticoid resistance. Hydrochlorothiazide effectively treats both acidosis and hyperkalemia by increasing potassium excretion.

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    Area of Science:

    • Nephrology
    • Endocrinology
    • Acid-Base Balance

    Background:

    • Type II pseudohypoaldosteronism is an autosomal dominant disorder characterized by hyperkalemic acidosis.
    • The precise cause of acidosis in this syndrome has remained unclear.
    • Previous studies suggest a potential defect in hydrogen ion secretion.