Nutritional considerations with antiobesity medications

Area of Science:

• Obesity Medicine
• Nutritional Science

Background:

• Emerging antiobesity medications (AOMs) demonstrate improved efficacy and safety.
• These medications achieve an average weight reduction of ≥15%, marking a significant advancement in obesity treatment.

Purpose of the Study:

• To offer evidence-based recommendations for nutritional assessment, management, and monitoring of patients undergoing AOM treatment.
• To guide clinicians in supporting patients to optimize health and well-being during AOM therapy.

Main Methods:

• This narrative review synthesizes current evidence on nutritional considerations for AOMs.
• Recommendations cover pre-treatment assessment, counseling on nutrient intake, and ongoing monitoring during AOM therapy.

Main Results:

• Pre-treatment assessment should identify nutritional risks and guide counseling on protein, fiber, micronutrients, and fluids.
• Ongoing monitoring is crucial for managing gastrointestinal symptoms and ensuring adequate nutrient/fluid intake.
• Holistic patient support should include physical activity, social, and emotional health aspects.

Conclusions:

• Clinicians play a vital role in supporting patients with obesity during AOM treatment.
• Optimizing nutritional status and addressing lifestyle factors enhance treatment response and quality of life.
• Comprehensive management promotes optimal nutritional and medical outcomes for patients on AOMs.