Related Experiment Video
Updated: Jun 24, 2025
09:31
Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model
Published on: October 2, 2015
9.2K
Surveillance for donor-derived infections in Australia
Helen Ingrid Opdam1,2, Peter Boan3,4, Lucinda Barry1
1Australian Organ and Tissue Authority, Canberra, Australia.
Summary
Australia
Area of Science:
- Organ donation and transplantation safety.
- Infectious disease surveillance.
Background:
- Quality and safety assurance systems are vital in organ donation and transplantation.
- Minimizing donor-derived disease transmission is a key focus.
- Australia implemented a national vigilance and surveillance system for donor-derived infections.
Purpose of the Study:
- To evaluate the effectiveness of Australia's national vigilance and surveillance system.
- To identify trends in donor-derived infections and diseases.
- To inform improvements in organ donation and transplantation processes and guidelines.
Main Methods:
- National notification of incidents to the Australian Organ and Tissue Authority.
- Review and grading of incidents by a Vigilance and Surveillance Expert Advisory Committee (VSEAC).
- Issuance of public and clinical communications and recommendations by VSEAC.
Main Results:
- Annual notifications increased from 2012 to 2022, primarily procedural.
- Donor-derived disease accounted for 19% of notifications; infections 12%.
- VSEAC recommendations led to revised donor screening, organ allocation, and clinical guidance for viral and infectious risks.
Conclusions:
- The Australian system enables national retrospective reporting and evaluation of adverse events.
- Identified trends inform processes and guidelines.
- The system demonstrably improves the safety of organ donation and transplantation.
