Related Experiment Video
Updated: Jun 24, 2025

A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information
Published on: July 1, 2020
Categorical linkage-data analysis
Li-Chun Zhang1, Tiziana Tuoto2
1Department of Social Statistics and Demography, University of Southampton, Southampton, UK.
Abstract:
Analysis of integrated data often requires record linkage in order to join together the data residing in separate sources. In case linkage errors cannot be avoided, due to the lack a unique identity key that can be used to link the records unequivocally, standard statistical techniques may produce misleading inference if the linked data are treated as if they were true observations. In this paper, we propose methods for categorical data analysis based on linked data that are not prepared by the analyst, such that neither the match-key variables nor the unlinked records are available. The adjustment is based on the proportion of false links in the linked file and our approach allows the probabilities of correct linkage to vary across the records without requiring that one is able to estimate this probability for each individual record. It accommodates also the general situation where unmatched records that cannot possibly be correctly linked exist in all the sources. The proposed methods are studied by simulation and applied to real data.
More Related Videos
08:43Application of Granger Causality Analysis of the Directed Functional Connection in Alzheimer's Disease and Mild Cognitive Impairment
Published on: August 7, 2017
08:27Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization
Published on: July 27, 2021
Related Concept Videos
How Data are Classified: Categorical Data
Data are classified based on whether they are measurable or not. Categorical data cannot be measured; instead, it can be divided into categories. For example, if Y denotes a person's party affiliation, some examples of Y include...
Criteria for Causality: Bradford Hill Criteria - II
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...
Nominal Level of Measurement
The data that cannot be measured but can be grouped into categories fall under the nominal level of measurement. Data that is measured using a nominal...
Bar Graph
Friedman Two-way Analysis of Variance by Ranks