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Updated: May 7, 2026
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A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva
Published on: July 5, 2017
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Pathogen Profiles of Infectious Conjunctivitis in Ho Chi Minh City, Vietnam
Huy Tran1, Linh Hoang1, Yen Tran1
1Hai Yen Vision Institute, Ho Chi Minh City, Vietnam.
Cornea Open
|June 10, 2024
Summary
Human adenoviruses are the primary cause of infectious conjunctivitis in Vietnam, with regional variations observed. The study also identified other pathogens like RNA viruses, highlighting the need for expanded surveillance.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Conjunctivitis outbreaks pose a significant global health challenge.
- Understanding the etiological agents of conjunctivitis is crucial for effective disease control.
Purpose of the Study:
- To comprehensively identify pathogens responsible for conjunctivitis in Vietnam.
- To investigate the diversity of infectious agents causing conjunctivitis in the region.
Main Methods:
- Prospective study of patients with acute conjunctivitis in Ho Chi Minh City, Vietnam (September 2022 - March 2023).
- Collection of conjunctival and anterior nasal swabs.
- Unbiased RNA deep sequencing (RNA-seq) for pathogen identification.
Main Results:
- Pathogens identified in 80% of 35 analyzed samples.
- Human Adenoviruses (HAdV-D and HAdV-B) were the most common cause (72%).
- Other detected pathogens included rhinoviruses, human coronavirus 229E, Streptococcus pneumoniae, Hemophilus influenza, Pseudomonas spp., and the fungus Vittaforma corneae.
Conclusions:
- Human adenoviruses are the predominant pathogens in Vietnamese conjunctivitis cases, with geographical variations in HAdV species.
- The detection of under-recognized pathogens like RNA viruses underscores the importance of broad pathogen surveillance.
- Findings suggest a need for enhanced monitoring of diverse microbial agents contributing to conjunctivitis.
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