Effect of boundary conditions in modeling of microsphere-assisted imaging

Exploring the performance of label-free imaging relies heavily on adequate physical models and accurate numerical simulations. A particularly challenging situation is imaging through contact microspheres, which have demonstrated resolution values exceeding the diffraction limit. Here an ab initio modeling of microsphere-assisted imaging is reported and its results are analyzed. The key part of modeling is solving the light scattering problem, which requires handling a rather large computational domain and broad angle illumination made up of multiple mutually incoherent plane waves. To account for plane wave incidence, two simulation approaches are developed that differ only by boundary conditions-quasiperiodic and absorbing. The algorithms to find images in both approaches are discussed and the simulation results are compared for free space and microsphere-assisted imaging. It is shown that while the super-resolution in microsphere-assisted imaging can be demonstrated using both approaches, the latter allows a large reduction in the computational resources. This significantly extends the capability of the simulations, enabling a rigorous exploration of novel imaging regimes.