Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cardiac Catheterization I: Pre-Procedure Overview01:28

Cardiac Catheterization I: Pre-Procedure Overview

Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
Cardiac Catheterization II: Right Heart Catheterization01:21

Cardiac Catheterization II: Right Heart Catheterization

Right Heart Catheterization: An OverviewRight heart catheterization is an invasive diagnostic procedure that measures right-sided cardiac and pulmonary artery pressures, calculates cardiac output, and identifies intracardiac shunts. It provides detailed hemodynamic data essential for diagnosing and managing various cardiovascular conditions, such as pulmonary hypertension.Access SitesCommon access sites for right heart catheterization include the internal jugular vein in the neck region, the...
Cardiac Catheterization III: Left Heart Catheterization01:24

Cardiac Catheterization III: Left Heart Catheterization

Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Incretin-based therapies and altered myocardial metabolism in a swine model of ischemic heart disease in the setting of metabolic syndrome.

Surgery·2026
Same author

Safe local management of mild traumatic brain injury: Reducing unnecessary transfers to higher-level trauma centers.

Surgery·2026
Same author

Association of cognitive impairment with statin use in coronary artery disease across APO (ε) genotypes in AllofUS.

medRxiv : the preprint server for health sciences·2026
Same author

Prediction of Cyanotic Congenital Heart Disease Risk in U.S. Births.

Journal of cardiovascular development and disease·2026
Same author

Linagliptin enhances coronary microvascular function and collateralization in a large animal model of cardiometabolic syndrome.

Microvascular research·2026
Same author

The interplay of diet and disease: High-fat feeding in chronic myocardial ischemia-A translational swine proteomics study.

Surgery·2026

Related Experiment Video

Updated: May 13, 2026

A Recovery Cardiopulmonary Bypass Model Without Transfusion or Inotropic Agents in Rats
09:54

A Recovery Cardiopulmonary Bypass Model Without Transfusion or Inotropic Agents in Rats

Published on: March 23, 2018

7.9K

Cardioprotection in cardiovascular surgery.

Sharif A Sabe1, Dwight D Harris1, Mark Broadwin1

  • 1Division of Cardiothoracic Surgery, Department of Surgery, Cardiovascular Research Center, Rhode Island Hospital, Rhode Island Hospital, Alpert Medical School of Brown University, 2 Dudley Street, MOC 360, Providence, RI, 02905, USA.

Basic Research in Cardiology
|June 10, 2024
PubMed
Summary

Improved cardioprotective strategies are crucial for complex cardiac surgeries. This review explores methods to reduce heart injury during cardiopulmonary bypass and enhance patient recovery.

Keywords:
CardioprotectionCardiopulmonary bypassCardiovascular surgery

More Related Videos

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model
08:22

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model

Published on: October 27, 2020

3.0K
Author Spotlight: Enhancing Coronary Artery Revascularization
05:25

Author Spotlight: Enhancing Coronary Artery Revascularization

Published on: September 15, 2023

694

Related Experiment Videos

Last Updated: May 13, 2026

A Recovery Cardiopulmonary Bypass Model Without Transfusion or Inotropic Agents in Rats
09:54

A Recovery Cardiopulmonary Bypass Model Without Transfusion or Inotropic Agents in Rats

Published on: March 23, 2018

7.9K
In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model
08:22

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model

Published on: October 27, 2020

3.0K
Author Spotlight: Enhancing Coronary Artery Revascularization
05:25

Author Spotlight: Enhancing Coronary Artery Revascularization

Published on: September 15, 2023

694

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Cardioprotection

Background:

  • Cardiopulmonary bypass (CPB) necessitates strategies to prevent myocardial ischemic injury.
  • Complex cardiac surgeries require enhanced cardioprotective measures for better patient outcomes.
  • Advances in surgical techniques and support systems increase the need for optimized cardioprotection.

Purpose of the Study:

  • To review fundamental cardioprotection principles in cardiac surgery.
  • To discuss current and novel strategies for optimizing cardioprotection.
  • To highlight translational research, including cell and gene therapy, for myocardial protection.

Main Methods:

  • Review of existing literature on cardioprotection mechanisms and strategies.
  • Discussion of refinements in CPB, cardioplegia, and anesthetic agents.
  • Exploration of ischemic conditioning, mechanical circulatory support, and cell/gene therapies.

Main Results:

  • Cardiac injury during CPB involves ischemia and reperfusion.
  • Optimizing cardioprotection involves refining CPB, cardioplegia, and pharmacological interventions.
  • Emerging cell-based and gene therapies show promise for myocardial protection.

Conclusions:

  • Effective cardioprotection is vital for managing complex cardiac surgical patients.
  • A multifaceted approach combining established and novel strategies is essential.
  • Future research in cell and gene therapy may significantly improve outcomes in cardiac surgery.