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Related Concept Videos

Bone Remodeling01:40

Bone Remodeling

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Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
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Osteoclasts in Bone Remodeling01:31

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Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
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Related Experiment Video

Updated: May 3, 2026

Osteoclast Derivation from Mouse Bone Marrow
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Erratum: A Simple Pit Assay Protocol to Visualize and Quantify Osteoclastic Resorption In Vitro.

Wanjing Cen1, Siegmar Reinert1, Meltem Avci-Adali2

  • 1Department of Oral and Maxillofacial Surgery, University Hospital Tübingen.

Journal of Visualized Experiments : Jove
|June 10, 2024
PubMed
Summary

This study corrects a previous article. The correction ensures the accuracy of scientific data and research findings for better reproducibility.

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Area of Science:

  • Scientific methodology
  • Research integrity

Background:

  • Correction of previously published research data.
  • Ensuring accuracy in scientific literature.

Discussion:

  • Addressing errors in the original publication.
  • Maintaining high standards in scientific reporting.

Key Insights:

  • Corrected data enhances research reliability.
  • Upholding the integrity of scientific findings.

Outlook:

  • Future research will benefit from accurate data.
  • Promoting transparency and correctness in scientific publications.