Related Experiment Video
Updated: Jun 24, 2025

Treatment of Facial Deformities using 3D Planning and Printing of Patient-Specific Implants
Published on: May 23, 2020
The Nasoorbitofrontal Complex in Facial Feminization Surgery
Tristan Beaufils1, Yanis Berkane1,2,3,4, Vlad Luca-Pozner5,6
1From the Department of Plastic, Reconstructive, and Aesthetic Surgery, Rennes University Hospital Center.
Background:
With the increasing demand for facial feminization surgery, there is a growing need for reliable and reproducible techniques to enhance outcomes. The authors aimed to evaluate the effectiveness of single-stage nasoorbitofrontal (NOF) complex reshaping in facial feminization surgery. Effectiveness was gauged by computed tomographic assessments and an unvalidated patient satisfaction survey at 6 months postoperatively.
Methods:
The study included 155 transfeminine patients undergoing surgery of the upper third of the face. Outcomes were compared in patients receiving either orbitofrontal (OF) surgery or combined NOF surgery. A comparative analysis of preoperative and postoperative standardized computed tomography sections was performed, focusing on multiple anatomic angles in 2 dimensions. A self-administered satisfaction questionnaire based on 6 FACE-Q items was completed at 6 months.
Results:
Among the 155 patients, 65 underwent OF surgery and 90 underwent NOF surgery. The follow-up period ranged from 6 to 36 months, with an average follow-up of 18 months. Significant changes in craniometric measurements were observed. In the OF group, average changes in nasofrontal, frontal tilt, and metopion angles were +12.3 ± 0.2 degrees, -8.5 ± 2.2 degrees, and +20.0 ± 0.1 degrees, respectively ( P < 0.001); in the NOF group, they were +28.5 ± 0.3 degrees, -9.3 ± 2.4 degrees, and +23.9 ± 0.1 degrees, respectively ( P < 0.001). The NOF group demonstrated higher overall satisfaction (median, 4 of 5) compared with the OF group (median, 3 of 5). No early complications were reported.
Conclusion:
The NOF complex surgery is an effective approach in gender-affirming surgery of the upper third of the face, yielding predictable results and higher patient satisfaction.
Clinical Question/Level Of Evidence:
Therapeutic, III.
Related Concept Videos
Association Areas of the Cortex
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Olfactory Receptors: Location and Structure
Psychosurgery
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
Muscles for Facial Expressions
Prosopagnosia
Olfaction
The olfactory receptors are embedded in the cilia of the...

