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Sphingomyelin-derived epacadostat nanovesicle enhances IDO1 inhibition for improved melanoma combination

Zhiren Wang1, Wenpan Li1, Jianqin Lu2,3,4,5

  • 1Skaggs Pharmaceutical Sciences Center, Department of Pharmacology & Toxicology, R. Ken Coit College of Pharmacy, The University of Arizona, Tucson, AZ, 85721, USA.

Genes and Immunity
|June 10, 2024
PubMed
Abstract

No abstract available in PubMed .

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Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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