Evaluation of enzyme immunosorbent rubella assays

Rubella enzyme-linked immunosorbent assays [( EIAs] Abbott Laboratories) were compared with hemagglutination inhibition methods in a national survey of clinical laboratories. Rubella EIAs demonstrated greater interlaboratory precision in screening for antibodies and better agreement among participants in quantification of antibody levels. From the viewpoint of interlaboratory surveys, EIA is well suited for routine use in clinical laboratories. The requirement for proper standardization of EIA was discussed.