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Updated: May 5, 2026

Methods for Acute and Subacute Murine Hindlimb Ischemia
Published on: June 21, 2016
A Free Bypass Flap for Chronic Limb-threatening Ischemia
Kohei Umekawa1, Takashi Kurabayashi1, Hirotaka Asato1
1From the Department of Plastic and Reconstructive Surgery, Dokkyo Medical University, Mibu, Tochigi, Japan.
Free bypass flaps improve foot circulation in chronic limb-threatening ischemia (CLTI) patients. This innovative technique offers a high bypass vessel patency rate, enhancing limb salvage for complex cases.
Area of Science:
- Vascular Surgery
- Reconstructive Surgery
Background:
- Inframalleolar disease is increasingly prevalent in chronic limb-threatening ischemia (CLTI) patients.
- Identifying adequate outflow vessels in the foot is challenging for these patients.
- Free tissue transfer is used, but concerns exist about impeding perfusion of diseased vascular beds.
Purpose of the Study:
- To introduce and evaluate the efficacy of a free bypass flap technique.
- To improve direct perfusion to the affected foot in CLTI patients.
Main Methods:
- Developed a "free bypass flap" combining free tissue transfer with bypass surgery.
- Performed bypass surgery by anastomosing a flap pedicle branch to a diseased foot artery.
- Conducted a retrospective chart review of nine CLTI patients (2018-2023).
Main Results:
- Achieved a 100% flap success rate (n=9).
- Demonstrated high bypass vessel patency (89%, n=8), confirmed by angiography/echo.
- Reported an 89% limb salvage rate (n=8).
Conclusions:
- Free bypass flap surgery enhances overall foot blood circulation.
- The technique shows a high patency rate for bypass vessels.
- It is a valuable method for limb preservation in highly comorbid CLTI patients.
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