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Oriented Graphene Oxide Scaffold Promotes Nerve Regeneration in vitro and in vivo [Response to Letter]

Xu Zhou1,2, Aolin Tang2,3, Chengjie Xiong2

  • 1The First School of Clinical Medicine, Southern Medical University, Guangzhou, 510515, People's Republic of China.

International Journal of Nanomedicine
|June 11, 2024
PubMed
Abstract

No abstract available in PubMed .

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In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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