Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Spinal Nerves: Anatomy01:23

Spinal Nerves: Anatomy

2.7K
Spinal nerves are pivotal conduits in the nervous system, bridging the central nervous system (CNS) with the peripheral nervous system (PNS). These nerves enable a complex communication network between the brain, spinal cord, and the rest of the body, facilitating sensory input, motor output, and autonomic functions.
There are 31 bilateral pairs of spinal nerves, each emerging from the spinal cord through the intervertebral foramina—openings between adjacent vertebrae. These nerves are...
2.7K
Spinal Nerves: Plexus II01:21

Spinal Nerves: Plexus II

555
The plexuses of the lower body include the lumbar, sacral, and coccygeal plexuses, which innervate the abdomen, pelvis, legs, and coccygeal region. These plexuses control the transmission of sensory information and coordinate motor functions of the lower body.
The Lumbar Plexus
The lumbar plexus is situated within the lumbar region of the back and is primarily formed by the first four lumbar spinal nerves (L1 to L4). This plexus extends its branches into several nerves, including the...
555
Spinal Cord: Cross-sectional Anatomy01:16

Spinal Cord: Cross-sectional Anatomy

1.8K
The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
Gray Matter and its Components
Central to the gray matter is...
1.8K
Arteries of Lower Limbs01:20

Arteries of Lower Limbs

1.4K
The external iliac artery transitions out of the body cavity, entering the femoral region of the lower leg, and is renamed the femoral artery at the point where it traverses the body wall. This artery is responsible for the distribution of blood to the thigh's deep muscles and the skin's ventral and lateral regions, achieved through several minor branches and the lateral deep femoral artery, which also spawns a lateral circumflex artery. The knee area receives blood from the genicular...
1.4K
The Spinal Cord01:54

The Spinal Cord

29.2K
The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
29.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction: Micheli et al. <i>Phaseolus vulgaris</i> L. Extract: Alpha-Amylase Inhibition Against Metabolic Syndrome in Mice. <i>Nutrients</i> 2019, <i>11</i>, 1778.

Nutrients·2026
Same author

Eduard Pernkopf's Atlas: morphological innovation and ethical legacy in the history of anatomical illustration.

Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie·2026
Same author

An integrated patient-derived colon organoids platform as a functional model for nutraceutical and stress response.

iScience·2026
Same author

Auricular hematoma in antiquity: Possible surgical drainage in the hellenistic boxer at rest.

The American journal of the medical sciences·2026
Same author

Early trifurcation of the facial artery including a dedicated buccinator branch: anatomical and surgical implications.

Case reports in plastic surgery & hand surgery·2026
Same author

A CT-Based Novel Way to Define Ethmoidal Foramina Topography in Human Orbits: Not So Variable After All.

The Journal of craniofacial surgery·2026

Related Experiment Video

Updated: Jun 24, 2025

Modified Spared Nerve Injury Surgery Model of Neuropathic Pain in Mice
04:34

Modified Spared Nerve Injury Surgery Model of Neuropathic Pain in Mice

Published on: January 25, 2022

4.7K

Sciatic Nerve and Its Anatomical Variations: In-Depth Understanding Acquired During Dissection Classes.

Jacopo Junio Valerio Branca1, Giulia Guarnieri1, Annamaria Morelli1

  • 1Experimental and Clinical Medicine, University of Firenze, Firenze, ITA.

Cureus
|June 11, 2024
PubMed
Summary

Understanding anatomical variations of the sciatic nerve (SN) and its relationship with the piriformis muscle (PM) is crucial for diagnosing pain and preventing surgical complications. This study details six unique cases of SN and PM anatomical variations observed during dissections.

Keywords:
anatomical variationsischiatic nervepiriformis musclepiriformis syndromesciatic nerve

More Related Videos

An In Vivo Murine Sciatic Nerve Model of Perineural Invasion
09:55

An In Vivo Murine Sciatic Nerve Model of Perineural Invasion

Published on: April 23, 2018

12.1K
Partial Sciatic Nerve Ligation: A Mouse Model of Chronic Neuropathic Pain to Study the Antinociceptive Effect of Novel Therapies
08:16

Partial Sciatic Nerve Ligation: A Mouse Model of Chronic Neuropathic Pain to Study the Antinociceptive Effect of Novel Therapies

Published on: October 6, 2022

6.2K

Related Experiment Videos

Last Updated: Jun 24, 2025

Modified Spared Nerve Injury Surgery Model of Neuropathic Pain in Mice
04:34

Modified Spared Nerve Injury Surgery Model of Neuropathic Pain in Mice

Published on: January 25, 2022

4.7K
An In Vivo Murine Sciatic Nerve Model of Perineural Invasion
09:55

An In Vivo Murine Sciatic Nerve Model of Perineural Invasion

Published on: April 23, 2018

12.1K
Partial Sciatic Nerve Ligation: A Mouse Model of Chronic Neuropathic Pain to Study the Antinociceptive Effect of Novel Therapies
08:16

Partial Sciatic Nerve Ligation: A Mouse Model of Chronic Neuropathic Pain to Study the Antinociceptive Effect of Novel Therapies

Published on: October 6, 2022

6.2K

Area of Science:

  • Anatomy
  • Neuroscience
  • Surgical Anatomy

Background:

  • Knowledge of anatomical variability is vital for understanding pain etiology and avoiding iatrogenic complications.
  • The sciatic nerve (SN), the largest peripheral nerve, originates from the lumbosacral plexus and passes near the piriformis muscle (PM).
  • Variability in the SN's course relative to the PM has been recognized for decades.

Observation:

  • This study documented six distinct anatomical variations of the SN and its interaction with the PM.
  • Observations were made during dissection classes using cadavers aged 58-84 years.
  • Variations included the SN's single or divided form (tibial nerve and common peroneal nerve) passing above, below, or through the PM.

Findings:

  • The sciatic nerve exhibited significant anatomical variability in its relationship with the piriformis muscle.
  • Observed variations involved the nerve's course (above, below, or through the muscle) and its division into tibial and common peroneal nerves.
  • The two nerve components could interact with the piriformis muscle in diverse ways, increasing anatomical complexity.

Implications:

  • A comprehensive understanding of sciatic nerve and piriformis muscle anatomical variations is essential for accurate diagnosis and effective treatment.
  • Knowledge of these variations aids in interpreting imaging, performing autopsies, and conducting surgeries.
  • Recognizing anatomical anomalies can lead to improved patient outcomes and reduced risk of surgical errors.