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Atypical BCR-ABL1 transcript in mixed phenotype acute leukemia with bone marrow necrosis

Jiarui Liu1, Yujie Jiang1, Dai Yuan1

  • 1Department of Hematology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.

Molecular Carcinogenesis
|June 11, 2024
PubMed
Summary

Philadelphia chromosome-positive (Ph+) mixed phenotype acute leukemia (MPAL) is rare. This case report details a patient with Ph+ MPAL and bone marrow necrosis, successfully treated with flumatinib and hyper-CVAD.

Keywords:
BCR‐ABL1Philadelphia chromosomeTKIatypical transcriptsmixed phenotype acute leukemia

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