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Updated: Jun 24, 2025

Author Spotlight: Advancing CBCT and Digital Dental Image Integration with AI-Assisted Digitization
Published on: February 23, 2024
Detection of oral cancer and oral potentially malignant disorders using artificial intelligence-based image analysis
Atsumu Kouketsu1, Chiaki Doi2, Hiroaki Tanaka2
1Division of Oral and Maxillofacial Oncology and Surgical Sciences, Department of Disease Management Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan.
Background:
We aimed to construct an artificial intelligence-based model for detecting oral cancer and dysplastic leukoplakia using oral cavity images captured with a single-lens reflex camera.
Subjects And Methods:
We used 1043 images of lesions from 424 patients with oral squamous cell carcinoma (OSCC), leukoplakia, and other oral mucosal diseases. An object detection model was constructed using a Single Shot Multibox Detector to detect oral diseases and their locations using images. The model was trained using 523 images of oral cancer, and its performance was evaluated using images of oral cancer (n = 66), leukoplakia (n = 49), and other oral diseases (n = 405).
Results:
For the detection of only OSCC versus OSCC and leukoplakia, the model demonstrated a sensitivity of 93.9% versus 83.7%, a negative predictive value of 98.8% versus 94.5%, and a specificity of 81.2% versus 81.2%.
Conclusions:
Our proposed model is a potential diagnostic tool for oral diseases.

