Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Patch Clamp

Patch Clamp

Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...

Drug Delivery: Miscellaneous Routes

Drug Delivery: Miscellaneous Routes

Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection, and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...

Bacterial Signaling

Bacterial Signaling

Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Ultrasound modulates microglial activity and reduces neuroinflammation in a parameter-dependent manner.

NPJ acoustics·2026

Same author

Comparison between SBMA and MPC coatings on PEEK surface: stability over time and anti-inflammatory effects in vitro.

Scientific reports·2025

Same author

Piezoelectric Chitosan Microporous Scaffolds for Ultrasound-Driven Schwann Cell Migration and Enhanced Neurotrophins Production.

ACS biomaterials science & engineering·2025

Same author

Soft robotics: what's next in bioinspired design and applications of soft robots?

Bioinspiration & biomimetics·2025

Same author

Biodegradable Piezoelectric Micro- and Nanomaterials for Regenerative Medicine, Targeted Therapy, and Microrobotics.

Small science·2025

Same author

Micropatterned Styrene-Butadiene-Styrene Thin Films Doped with Barium Titanate Nanoparticles: Effects on Myoblast Differentiation.

ACS biomaterials science & engineering·2025

Search research articles

Related Experiment Video

Updated: Jun 24, 2025

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Published on: October 20, 2021

Triggerable Patches for Medical Applications.

Sofia Sirolli^1,2, Daniele Guarnera^1,2, Leonardo Ricotti^1,2

¹The BioRobotics Institute, Scuola Superiore Sant'Anna, Piazza Martiri della Libertà 33, Pisa, 56127, Italy.

Advanced Materials (Deerfield Beach, Fla.)

|June 11, 2024

Summary

Triggerable medical patches offer precise drug delivery and tissue regeneration. This review explores stimuli-responsive patch technology, its applications, and current challenges for advanced therapies.

Keywords:

biophysical stimuli drug delivery smart medical patches tissue regeneration triggerable systems

More Related Videos

Author Spotlight: Innovative Microneedle-Based Strategies for Enhanced Exosome Delivery and Stability

Author Spotlight: Innovative Microneedle-Based Strategies for Enhanced Exosome Delivery and Stability

Published on: July 12, 2024

$Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain$

Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain

Published on: May 10, 2017

Related Experiment Videos

Last Updated: Jun 24, 2025

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Published on: October 20, 2021

Author Spotlight: Innovative Microneedle-Based Strategies for Enhanced Exosome Delivery and Stability

Author Spotlight: Innovative Microneedle-Based Strategies for Enhanced Exosome Delivery and Stability

Published on: July 12, 2024

$Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain$

Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain

Published on: May 10, 2017

Area of Science:

Biomedical Engineering
Materials Science
Pharmacology

Background:

Medical patches are increasingly utilized for diagnostics and therapeutics.
Advancements in materials, manufacturing, and bioengineering enhance patch functionality for wearable and implantable uses.
Triggerable patches, controlled by external signals, are of significant interest for drug delivery and tissue regeneration.

Purpose of the Study:

To provide a comprehensive review of triggerable patch literature.
To emphasize the potential of these patches in diverse applications.
To highlight the strengths and weaknesses of various triggering stimuli.

Main Methods:

Literature review of existing research on triggerable medical patches.
Analysis of different triggering stimuli and their properties.
Identification of current challenges in patch design and application.

Main Results:

Stimuli-responsive patches offer high temporal and spatial control for precise therapy.
Diverse applications exist for triggerable patches in medicine.
Various triggering stimuli present unique advantages and disadvantages.

Conclusions:

Triggerable patches hold significant potential for advanced therapeutic applications.
Key challenges include optimizing mechanical properties, biocompatibility, portability, and responsiveness.
Further research is needed to maximize therapeutic efficacy and clinical translation.