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Updated: Jun 24, 2025

A Nonviral Approach to Generate Transient Chimeric Antigen Receptor T Cells Using mRNA for Cancer Immunotherapy
Published on: February 21, 2025
Personalized cancer T-cell therapy takes the stage, mirroring vaccine success
Johanna Chiffelle1,2,3, Alexandre Harari1,2,3
1Department of Oncology, Ludwig Institute for Cancer Research, Lausanne Branch, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Abstract:
Personalized T-cell therapy is emerging as a pivotal treatment of cancer care by tailoring cellular therapies to individual genetic and antigenic profiles, echoing the exciting success of personalized vaccines. We describe here the parallel evolution and analogies of cancer vaccines and T-cell therapies.
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