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Post-infectious pityriasis rubra pilaris in pediatric patients

Javier Arellano1,2, Catalina Melehuechun2

  • 1Department of Dermatology, Hospital Clínico San Borja Arriarán, Santiago de Chile, Chile.

Archivos Argentinos De Pediatria
|June 11, 2024
PubMed

Insights

Pityriasis rubra pilaris (PRP), a rare skin disorder, may be triggered by respiratory syncytial virus (RSV) infection in children. Treatment with topical therapies led to PRP resolution in these cases.

Area of Science:

  • Dermatology
  • Pediatrics
  • Infectious Diseases

Background:

  • Pityriasis rubra pilaris (PRP) is a rare, chronic skin disorder of unknown etiology.
  • PRP has been linked to various triggers including infections, autoimmune conditions, and neoplasms.
  • Understanding PRP triggers is crucial for effective pediatric patient management.

Observation:

  • This report details two pediatric cases of Pityriasis rubra pilaris.
  • Both patients presented with concurrent respiratory syncytial virus (RSV) infection and obstructive bronchial syndrome.
  • The clinical presentation suggests a potential link between RSV infection and PRP development in children.

Findings:

  • Pityriasis rubra pilaris (PRP) diagnosis was confirmed in both pediatric patients.
  • A concurrent diagnosis of respiratory syncytial virus (RSV) infection with obstructive bronchial syndrome was noted.
  • PRP symptoms resolved following treatment with topical emollients, topical corticosteroids, and calcineurin inhibitors.

Implications:

  • Respiratory syncytial virus (RSV) infection may act as a trigger for Pityriasis rubra pilaris (PRP) in pediatric patients.
  • This finding expands the known potential triggers for PRP.
  • Effective management of pediatric PRP may involve addressing underlying infections and utilizing targeted topical therapies.

Keywords:
corticosteroids, calcineurin inhibitorsemollientspityriasis rubra pilarisrespiratory syncytial virus

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