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Updated: Jun 24, 2025

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Published on: October 31, 2010
A Multicomponent Intervention (POSSIBLE) to Improve Perceived Risk for HIV Among Black Sexual Minority Men:
Derek T Dangerfield Ii1, Janeane N Anderson2, Charleen Wylie1
1Milken Institute School of Public Health, George Washington University, Washington, DC, United States.
The POSSIBLE intervention, combining peer support and a smartphone app, showed feasibility but did not significantly increase perceived HIV risk in Black sexual minority men. Further research is needed to improve PrEP uptake.
Area of Science:
- Public Health
- Behavioral Science
- Digital Health
Background:
- Pre-exposure prophylaxis (PrEP) use is critical for reducing HIV incidence among Black sexual minority men.
- Low perceived risk for HIV (PRH) is a significant barrier to PrEP adoption in this population.
- Multicomponent interventions integrating peer support and digital tools are under-explored.
Purpose of the Study:
- To assess the feasibility and preliminary impact of the POSSIBLE intervention on PRH.
- To evaluate willingness to accept PrEP referrals among Black sexual minority men.
- To explore the combined use of a peer change agent (PCA) and the PrEPme app.
Main Methods:
- A pilot study involving 69 Black sexual minority men in Baltimore, MD (2019-2021).
- Integration of a PCA with the PrEPme smartphone app for self-monitoring and health worker interaction.
- Assessment of PRH using an 8-item scale pre- and post-intervention; referral to PrEP services.
Main Results:
- High retention rate (80%) at 1-month follow-up.
- 42% of participants were willing to be referred for PrEP services, with 69% scheduling appointments.
- No statistically significant change in PRH was observed between baseline and follow-up (P=.17).
Conclusions:
- The POSSIBLE intervention demonstrated feasibility and acceptability among participants.
- While PRH did not significantly improve, the intervention shows promise for engagement.
- Future research should focus on statistically powered, peer-based strategies to enhance PrEP initiation.
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