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Updated: Jun 24, 2025

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Testing dilemmas in the clinic: Lessons learned from biomarker-based drug development

Sahar Barjesteh van Waalwijk van Doorn-Khosrovani1, Olga Kholmanskikh Van Criekingen2, Simone Koole3

  • 1Department of Medical Oncology, Leiden University Medical Centre, Leiden, the Netherlands; Medical Department, CZ Health Insurance, Tilburg, the Netherlands.

Cancer Cell
|June 11, 2024
PubMed
Summary

Standardizing complex biomarkers for poly(ADP-ribose) polymerase (PARP)-inhibitor therapy is crucial. This study proposes measures for harmonized definitions and performance standards to ensure equitable precision medicine access.

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