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Case Report: Neurobrucellosis Presenting as Malignancy
Andrea S Salcedo1, Xosse Carreras1, Takaaki Kobayashi2
1Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Abstract:
Neurobrucellosis, caused by Brucella species, is a zoonotic infection that may involve the central nervous system. Although uncommon, it can manifest as a solitary intracranial mass. We report a case of neurobrucellosis in a 25-year-old woman from Peru who presented with headache, weight loss, and right-side hemiparesis and paresthesia. A contrast-enhanced magnetic resonance imaging scan revealed an intracerebral mass in the left temporal lobe. Serum testing subsequently were positive. Brain biopsy demonstrated non-necrotizing granulomas without malignant cells. Neurobrucellosis should be considered in the differential diagnosis of brain space occupying lesions in endemic countries.
Insights
Neurobrucellosis, a rare central nervous system infection, can mimic brain tumors. Early consideration of this zoonotic disease is crucial for patients presenting with intracranial masses in endemic regions.
Area of Science:
- Infectious Diseases
- Neurology
- Zoonotic Infections
Background:
- Neurobrucellosis is a rare central nervous system (CNS) infection caused by Brucella species.
- It can present atypically as a solitary intracranial mass, posing diagnostic challenges.

