Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cancer Survival Analysis01:21

Cancer Survival Analysis

343
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
343
Cancer Stem Cells and Tumor Maintenance02:40

Cancer Stem Cells and Tumor Maintenance

4.9K
Early diagnosis and treatment can often cure cancer. However, even with treatment, residual cells called cancer stem cells (CSC) might remain, often causing tumor recurrence. These cancer stem cells possess the potential for self-renewal and multi-lineage differentiation and are often responsible for the therapeutic resistance displayed in most cancers.
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...
4.9K
mTOR Signaling and Cancer Progression03:03

mTOR Signaling and Cancer Progression

3.8K
The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...
3.8K
The Tumor Microenvironment02:17

The Tumor Microenvironment

6.6K
Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
6.6K
Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

5.5K
Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
5.5K
  1. Home
  2. Research Domains
  3. Biomedical And Clinical Sciences
  4. Oncology And Carcinogenesis
  5. Predictive And Prognostic Markers
  6. "let Him Die. He Caused It": A Qualitative Study On Cancer Stigma In Tanzania.
  1. Home
  2. Research Domains
  3. Biomedical And Clinical Sciences
  4. Oncology And Carcinogenesis
  5. Predictive And Prognostic Markers
  6. "let Him Die. He Caused It": A Qualitative Study On Cancer Stigma In Tanzania.

Related Experiment Video

Dried Blood and Serum Spots As A Useful Tool for Sample Storage to Evaluate Cancer Biomarkers
08:44

Dried Blood and Serum Spots As A Useful Tool for Sample Storage to Evaluate Cancer Biomarkers

Published on: June 11, 2018

10.5K

"Let him die. He caused it": A qualitative study on cancer stigma in Tanzania.

Judith M Mwobobia1, Brandon A Knettel1,2, Jennifer Headley1

  • 1Duke Global Health Institute, Duke University, Durham, North Carolina, United States of America.

PLOS Global Public Health
|June 12, 2024

View abstract on PubMed

Summary
This summary is machine-generated.

Cancer stigma in Tanzania, driven by financial fears and misconceptions, significantly hinders care-seeking and treatment adherence. Interventions must address literacy, community attitudes, and affordability to improve cancer outcomes.

More Related Videos

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
07:14

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery

Published on: January 18, 2018

9.3K
A Sensitive Method to Quantify Senescent Cancer Cells
09:18

A Sensitive Method to Quantify Senescent Cancer Cells

Published on: August 2, 2013

20.7K

Related Experiment Videos

Dried Blood and Serum Spots As A Useful Tool for Sample Storage to Evaluate Cancer Biomarkers
08:44

Dried Blood and Serum Spots As A Useful Tool for Sample Storage to Evaluate Cancer Biomarkers

Published on: June 11, 2018

10.5K
A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
07:14

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery

Published on: January 18, 2018

9.3K
A Sensitive Method to Quantify Senescent Cancer Cells
09:18

A Sensitive Method to Quantify Senescent Cancer Cells

Published on: August 2, 2013

20.7K

Area of Science:

  • Oncology
  • Public Health
  • Sociology

Background:

  • Cancer is the third-leading cause of death in Tanzania, with rising incidence and poor outcomes.
  • Cancer-related stigma is a significant barrier to care seeking, treatment adherence, and patient support.
  • Interventions to reduce cancer stigma have been historically under-prioritized in Tanzania.

Purpose of the Study:

  • To explore attitudes driving cancer stigma in Tanzania.
  • To understand the impact of cancer stigma on care-seeking and treatment adherence.
  • To identify potential intervention strategies for reducing cancer stigma.

Main Methods:

  • A cross-sectional qualitative study design was employed.
  • 140 adults newly diagnosed with cancer in Moshi, Tanzania, were interviewed using open-ended questions.
  • Data analysis utilized a team-based, applied thematic approach with NVivo 12 software.
  • Main Results:

    • Participants identified financial burden, misconceptions (e.g., cancer being contagious), and fear of death as key drivers of stigma.
    • Stigma led to shame, fear of burdening families, reduced access to treatment, and disengagement from care.
    • Some patients reported increased social support post-diagnosis, indicating stigma is not universally experienced.

    Conclusions:

    • Addressing cancer stigma requires interventions focused on improving cancer literacy, community advocacy, and enhancing emotional/practical support.
    • Financial support, professional counseling, and community education are crucial for reducing stigmatizing attitudes.
    • Policy changes to improve cancer care affordability and accessibility are essential to alleviate patient and family financial burdens.