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Opportunistic population screening as a hepatitis elimination strategy: the CRIVALVIR-FOCUS program
Enrique Ortega González1, María Dolores Ocete Mochón2, Concepción Gimeno Cardona2
1Fundación de Investigación Hospital General Universitario de Valencia. Universidad de Valencia. Valencia, Spain.
Summary
Opportunistic screening effectively identified undiagnosed Hepatitis B (HBV) and Hepatitis C (HCV) infections in Spain. Targeted interventions for migrants and individuals aged 45-64 are crucial for viral hepatitis elimination.
Area of Science:
- Hepatology
- Public Health
- Infectious Diseases
Background:
- Hepatitis B (HBV) and hepatitis C (HCV) are leading causes of liver cancer, resulting in over a million deaths annually.
- Viral hepatitis elimination is a global public health priority, with the WHO setting ambitious 2030 targets.
Purpose of the Study:
- To develop and evaluate a screening strategy for viral hepatitis elimination in Spain.
- To identify individuals with active blood-borne viral infections through opportunistic screening.
Main Methods:
- The CRIVALVIR-FOCUS program conducted opportunistic screening at the Consortium General University Hospital of Valencia.
- Over 31,000 adults were screened, with data collected on demographics and viral infection status.
Main Results:
- HBV prevalence was 0.44% and HCV prevalence was 0.35%.
- Prevalence was higher in men, migrants, and the 45-64 age group for both viruses.
- A significant proportion of positive cases (78% for HBV, 71% for HCV) were previously unaware of their infection.
Conclusions:
- Opportunistic screening is effective in detecting early, undiagnosed viral hepatitis cases.
- Targeted screening and interventions are needed for high-risk groups, including migrants and individuals aged 45-64.
- Collaboration with social workers, cultural mediators, and primary care professionals is essential for successful program implementation.
