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Updated: Jun 24, 2025

A Murine Tail Lymphedema Model
Published on: February 10, 2021
A 53-year-old Man with Idiopathic Bilateral Chylothorax Refractory to Lymphaticovenular Anastomosis
Tomoko Yamada1, Koji Sugano1, Kei Matsuno1
1Department of Respiratory Medicine, Juntendo Tokyo Koto Geriatric Medical Center, Japan.
Abstract:
A 53-year-old man with chronic dyspnea and bilateral pleural effusion was subsequently diagnosed with idiopathic chylothorax. Lymphatic scintigraphy confirmed lymphatic fluid leakage at the left venous angle, prompting management with lymphaticovenular anastomosis (LVA). Although the left pleural effusion was controlled, the right pleural effusion continued to increase, resulting in bilateral leg lymphedema that was refractory to LVA. Approximately three years and three months after the presentation, the patient succumbed to CO2 narcosis and renal failure. It is crucial to study additional cases in order to uncover new causes and develop pathology-based treatments for this condition.
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