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Association between obstructive sleep apnea (OSA) and COVID-19 severity
Oria Nassi-Liberman1, Bernice Oberman2, Tamar Strahl2
1Adelson School of Medicine, Ariel University, Ariel, Israel.
Journal of Sleep Research
|June 12, 2024
Summary
Obstructive sleep apnea increases the risk of severe Coronavirus disease 2019 (COVID-19) but not mortality. Higher socioeconomic status is linked to increased severe COVID-19 and mortality risk.
Area of Science:
- Medicine
- Public Health
- Epidemiology
Background:
- Obstructive sleep apnea (OSA) and sleep-related hypoxia are linked to worse outcomes in Coronavirus disease 2019 (COVID-19).
- Understanding risk factors for COVID-19 severity and mortality is crucial for public health strategies.
Purpose of the Study:
- To investigate the association between obstructive sleep apnea (OSA) and COVID-19 severity and mortality.
- To examine the impact of clinical and demographic factors, including socioeconomic status, on COVID-19 outcomes.
Main Methods:
- Retrospective study of 44,275 adult patients diagnosed with COVID-19 before the Omicron variant.
- Comparison of COVID-19 severity and mortality between patients with and without OSA.
- Multivariate analysis to identify independent risk factors for severe COVID-19 and mortality.
Main Results:
- OSA diagnosis was associated with a 1.6 times higher risk of severe COVID-19 compared to mild disease.
- No significant increase in COVID-19 mortality was observed in patients with OSA.
- Higher socioeconomic status correlated with increased risk of severe COVID-19, morbidity, and mortality.
Conclusions:
- Obstructive sleep apnea is an independent risk factor for severe COVID-19.
- Socioeconomic status significantly influences COVID-19 severity and mortality, with higher status posing greater risk.
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