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Updated: Jun 24, 2025

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine
Published on: February 24, 2023
Unresectable cardiac metastasis from melanoma responds well to combination immunotherapy-a case report
Ek Leone Oh1, Peter Dias2,3, Zeyad Al-Ogaili4
1Medical Oncology Department, Fiona Stanley Hospital, 11 Robin Warren Drive, Murdoch, WA 6150, Australia.
Background:
Melanoma can metastasize to distal organs including the heart although presentation with a symptomatic cardiac metastasis is rare. The optimal management remains uncertain particularly in the era of immunotherapy.
Case Summary:
We report a case presenting with a large unresectable cardiac metastasis from melanoma that responded well to treatment with immunotherapy.
Conclusion:
Melanoma can metastasize to the heart and is often challenging to diagnose. Combination immunotherapy can be an effective treatment option even in the setting of a symptomatic and unresectable cardiac metastasis.
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