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TOmicsVis: An all-in-one transcriptomic analysis and visualization R package with Shinyapp interface.

Ben-Ben Miao1, Wei Dong2, Zhao-Fang Han1

  • 1State Key Laboratory of Marine Environmental Science, College of Ocean and Earth Sciences Xiamen University Xiamen China.

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|June 13, 2024
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Summary
This summary is machine-generated.

Researchers can now easily analyze and visualize transcriptomic data with TOmicsVis, an R package simplifying complex multigroup experiments. This tool integrates features from multiple R packages for streamlined biological mechanism discovery.

Keywords:
data visualizationdifferential expressionenrichment analysismultigroup RNA‐Seqshinyapp

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Area of Science:

  • Bioinformatics
  • Genomics
  • Computational Biology

Background:

  • Transcriptomic analysis is crucial for understanding biological mechanisms across species.
  • Existing R packages for transcriptomics lack unified integration and user-friendly interfaces for complex analyses.

Purpose of the Study:

  • To develop a comprehensive R package, TOmicsVis (Transcriptomics Visualization), for streamlined transcriptomics data analysis and visualization.
  • To provide a user-friendly solution integrating features from multiple R packages for multigroup transcriptomic projects.

Main Methods:

  • Developed TOmicsVis, an R package utilizing 46 other R packages.
  • Implemented 40 functions covering Sample Statistics, Traits Analysis, Differential Expression, Advanced Analysis, GO and KEGG Enrichment, and Table Operation.
  • Enabled both local and online (Shiny app) execution for accessibility.

Main Results:

  • TOmicsVis offers a unified platform for transcriptomics analysis and visualization.
  • The package streamlines multigroup transcriptomic projects with diverse analytical functions.
  • Provides accessible tools for researchers with and without coding expertise.

Conclusions:

  • TOmicsVis enhances the efficiency and accessibility of transcriptomics data analysis.
  • Facilitates prompt monitoring of experimental data dynamics and rapid exploration of transcriptomics data.
  • Empowers researchers to uncover biological mechanisms more effectively.