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Related Concept Videos

Inheritance

Inheritance

Gregor Mendel's pioneering work on the principles of inheritance fundamentally transformed our understanding of how traits are transmitted from generation to generation. His experiments with pea plants laid the groundwork for the discovery of genes, discrete units within organisms that control heredity.
Each gene exists in pairs, and the combination of these genes from both parents forms an individual's genotype. This genotype is a blueprint of potential traits. Examples of genotype...

Pedigree Analysis

Pedigree Analysis

Law of Segregation

Law of Segregation

When crossing pea plants, Mendel noticed that one of the parental traits would sometimes disappear in the first generation of offspring, called the F1 generation, and could reappear in the next generation (F2). He concluded that one of the traits must be dominant over the other, thereby causing masking of one trait in the F1 generation. When he crossed the F1 plants, he found that 75% of the offspring in the F2 generation had the dominant phenotype, while 25% had the recessive phenotype.

Genomic Imprinting and Inheritance

Genomic Imprinting and Inheritance

Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...

Chromosomal Theory of Inheritance

Chromosomal Theory of Inheritance

In 1866, Gregor Mendel published the results of his pea plant breeding experiments, providing evidence for predictable patterns in the inheritance of physical characteristics. The significance of his findings was not immediately recognized. In fact, the existence of genes was unknown at the time. Mendel referred to hereditary units as “factors.”

Probability Laws

Probability Laws

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Related Experiment Video

Updated: Jun 24, 2025

High-throughput Screening for Protein-based Inheritance in S. cerevisiae

High-throughput Screening for Protein-based Inheritance in S. cerevisiae

Published on: August 8, 2017

From parent to progeny.

Sara Shama¹, Michelle R Asbury², Deborah L O'Connor³

¹Department of Nutritional Sciences, University of Toronto, Toronto, Canada; Translational Medicine Program, SickKids Research Institute, The Hospital for Sick Children, Toronto, Canada.

Cell Host & Microbe

|June 13, 2024

Summary

The infant gut microbiome is shaped by parental microbes. Understanding this transmission is key to infant health and development.

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Last Updated: Jun 24, 2025

High-throughput Screening for Protein-based Inheritance in S. cerevisiae

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Published on: August 8, 2017

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Author Spotlight: RNAi Inheritance and ChIP in C. elegans

Author Spotlight: RNAi Inheritance and ChIP in C. elegans

Published on: May 5, 2023

Area of Science:

Microbiology
Human Microbiome
Pediatrics

Background:

The establishment of the infant gut microbial community is crucial for immune system development and overall health.
Factors influencing the transmission of microbes from parents to infants are not fully understood.

Purpose of the Study:

To investigate the transmission dynamics of microbial communities from parents to infants.
To identify key factors that modify the infant gut microbiome composition during early life.

Main Methods:

Utilized shotgun metagenomic sequencing to analyze microbial DNA from parent and infant samples.
Employed advanced bioinformatics to assess microbial community structure and identify sources of transmission.

Main Results:

Demonstrated direct transmission of specific microbial species from mothers and fathers to their infants.
Identified delivery mode and early-life exposures as significant modulators of infant gut microbial colonization.

Conclusions:

Parental microbial seeding plays a critical role in shaping the infant gut microbiome.
Environmental and lifestyle factors interact with genetic predisposition to influence infant microbial community development.