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Updated: Jun 24, 2025

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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Chloranthalactone B covalently binds to the NACHT domain of NLRP3 to attenuate NLRP3-driven inflammation

Pengfei Tang1, Shuai Zhao1, Xiaoli Wang1

  • 1State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, People's Republic of China.

Biochemical Pharmacology
|June 13, 2024
PubMed

Keywords:
Chloranthalactone BCovalent bindEpoxide motifNACHT domainSarcandra glabra

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