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Updated: Jun 24, 2025

FRET Imaging in Three-dimensional Hydrogels
Published on: August 1, 2016
Supramolecular Hydrogels for 3D Biosensors and Bioassays
Paola Gagni1, Giulia Lodigiani1, Roberto Frigerio1
1Istituto di Scienze e Tecnologie Chimiche "Giulio Natta", National Research Council of Italy (SCITEC-CNR), 20131, Milan, Italy.
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Supramolecular hydrogels play a pivotal role in many fields of biomedical research, including emerging applications in designing advanced tools for point-of-care testing, clinical diagnostics, and lab-on-chip analysis. This review outlines the growing relevance of supramolecular hydrogels in biosensing and bioassay devices, highlighting recent advancements that deliver increased sensitivity, real-time monitoring, and multiplexing capabilities through the distinctive properties of these nanomaterials. Furthermore, the exploration extends to additional applications, such as using hydrogels as three-dimensional matrices for cell-based assays.

