Isobutane, Isopentane, Butane, and Propane
Regina Tucker1, Wilma F Bergfeld2, Donald V Belsito2
1Cosmetic Ingredient Review Former Scientific Analyst/Writer.
International Journal of Toxicology
|June 14, 2024
Summary
The Expert Panel for Cosmetic Ingredient Safety reaffirms that Isobutane, Isopentane, Butane, and Propane are safe for cosmetic use. This conclusion is based on reviews conducted in 1982, 2002, and most recently in 2023.
Area of Science:
- Cosmetic Science
- Toxicology
- Chemical Safety Assessment
Background:
- The Expert Panel for Cosmetic Ingredient Safety (Panel) initially assessed Isobutane, Isopentane, Butane, and Propane in 1982.
- Previous reviews in 2002 reaffirmed the safety of these ingredients in cosmetic applications.
Purpose of the Study:
- To conduct a re-review of the safety of Isobutane, Isopentane, Butane, and Propane.
- To evaluate newly available safety data and update frequency and concentration of use information.
Main Methods:
- Review of existing safety data from 1982 and 2005.
- Assessment of updated information on ingredient usage and newly published safety data from 2023.
Main Results:
- The Panel considered updated safety data, concentration of use, and frequency of use information.
- All available data were evaluated in the context of previous safety assessments.
Conclusions:
- The Expert Panel for Cosmetic Ingredient Safety reaffirmed the 1982 conclusion regarding the safety of Isobutane, Isopentane, Butane, and Propane.
- These ingredients remain considered safe for cosmetic use under current conditions.
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