Asymptomatic Systemic Mastocytosis Uncovered During Routine Colonoscopy: A Case Report

Area of Science:

• Gastroenterology
• Oncology
• Hematology

Background:

• Systemic mastocytosis (SM) is a rare disorder characterized by abnormal mast cell proliferation.
• While often symptomatic, SM can present atypically, posing diagnostic challenges.

Observation:

• A 66-year-old asymptomatic female was incidentally diagnosed with systemic mastocytosis during a routine colonoscopy.
• Subtle abnormalities noted during the endoscopic procedure prompted further investigation.

Findings:

• The incidental diagnosis highlights the diverse clinical spectrum of systemic mastocytosis.
• Histopathological examination of endoscopic biopsies was crucial for confirming the diagnosis.

Implications:

• This case emphasizes the diagnostic value of colonoscopy in detecting unexpected systemic diseases.
• Routine endoscopic procedures require meticulous histopathological evaluation, even in asymptomatic patients with subtle findings.