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Published on: July 23, 2016
A review of the efficacy of popular eye cream ingredients
Hanin Hamie1, Reem Yassine1, Rajaa Shoukfeh2
1College of Osteopathic Medicine, Michigan State University, East Lansing, Michigan.
Background:
Due to the periorbital region's high susceptibility to damage from external factors, along with its tendency to demonstrate early signs of aging, periorbital skin is a common target for antiaging therapy.
Objective:
This review aims to evaluate the efficacy of active ingredients commonly found in eye creams, particularly focusing on their impact on periorbital skin concerns.
Methods:
A comprehensive review of the literature on active ingredients in eye creams, including retinoids, vitamins C and E, peptides, ceramides, hyaluronic acid, caffeine, and niacinamide, was conducted. Clinical studies assessing the efficacy of these ingredients in addressing periorbital concerns were examined.
Results:
Studies demonstrate the potential of these ingredients to improve various aspects of periorbital skin, including hydration, elasticity, collagen synthesis, and reduction of inflammatory mediators. Ingredients such as retinoids, vitamin C, and caffeine show promise in addressing wrinkles and hyperpigmentation, while peptides and hyaluronic acid aid in collagen production and hydration. Niacinamide and ceramides offer benefits in reducing wrinkles and enhancing the skin barrier function.
Limitations:
The lack of clinical trials specifically targeting eye cream formulations and periorbital skin is a notable limitation. Furthermore, the variability in study designs, sample sizes, and concentrations of active ingredients across studies complicates direct comparisons.
Conclusion:
The reviewed studies highlight the potential of active ingredients in eye creams to address various periorbital concerns. Further research, particularly large-scale clinical trials focusing on eye cream formulations and their efficacy on periorbital skin, is warranted to establish their significance and comparability with other dermatologic products.
Insights
Active ingredients in eye creams can improve periorbital skin concerns like wrinkles and hydration. Further research is needed to confirm their efficacy in specific eye cream formulations.
Area of Science:
- Dermatology
- Cosmetic Science
Background:
- Periorbital skin is prone to aging and external damage, making it a key area for anti-aging treatments.
- Eye creams are frequently used to address these periorbital skin concerns.
Purpose of the Study:
- To review the efficacy of common active ingredients found in eye creams.
- To assess their impact on periorbital skin aging and related issues.
Main Methods:
- A literature review was conducted on active ingredients like retinoids, vitamins C and E, peptides, ceramides, hyaluronic acid, caffeine, and niacinamide.
- Clinical studies evaluating these ingredients for periorbital concerns were examined.
Main Results:
- Ingredients show potential for improving periorbital skin hydration, elasticity, and collagen synthesis.
- Retinoids, vitamin C, and caffeine target wrinkles and hyperpigmentation; peptides and hyaluronic acid boost collagen and hydration; niacinamide and ceramides enhance skin barrier function.
Conclusions:
- Active ingredients in eye creams demonstrate potential for addressing periorbital concerns.
- Further large-scale clinical trials on specific eye cream formulations are necessary to confirm efficacy and comparability.

