High Uptake of Respiratory Syncitial Virus Prevention for Neonates in a Military Treatment Facility

Richelle L Homo1, Andrew Groberg1, Megan Donahue2

  • 1Brooke Army Medical Center, Division of Neonatal and Perinatal Medicine, Department of Pediatrics, San Antonio, TX.

PubMed

Insights

High uptake of nirsevimab for infants and the RSVPreF vaccine for pregnant individuals was observed during birth hospitalizations. These findings support RSV prevention strategies for future seasons.

Area of Science:

  • Pediatrics
  • Immunology
  • Public Health

Background:

  • Respiratory Syncytial Virus (RSV) is a significant cause of infant respiratory illness.
  • Effective prevention strategies are crucial for protecting vulnerable infants.
  • Nirsevimab and maternal RSV vaccination are key interventions.

Purpose of the Study:

  • To evaluate the uptake of nirsevimab in infants.
  • To assess the uptake of the bivalent RSVPreF vaccine in pregnant individuals.
  • To determine the effectiveness of these interventions during birth hospitalization.

Main Methods:

  • Retrospective analysis of medical records in a military treatment facility.
  • Tracking nirsevimab administration to infants.
  • Monitoring RSVPreF vaccine administration to pregnant persons.
  • Data collected from October 2023 to February 2024.

Main Results:

  • Achieved over 85% uptake for both nirsevimab in infants and the RSVPreF vaccine in pregnant individuals.
  • Demonstrated high acceptance rates during the birth hospitalization period.
  • Indicated successful implementation of RSV prevention measures.

Conclusions:

  • Nirsevimab and maternal RSV vaccination show high uptake in military healthcare settings.
  • These interventions can be effectively delivered during infant birth hospitalizations.
  • Findings provide valuable insights for planning future RSV prevention campaigns.

Related Concept Videos

Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
1.2K
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
206
Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
132
Pneumonia V: Nursing management and Prevention01:30

Pneumonia V: Nursing management and Prevention

Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
2.0K
Acute Respiratory Failure-I01:21

Acute Respiratory Failure-I

Acute respiratory failure is a condition characterized by the inability of the lungs to perform their primary function: gas exchange. This failure leads to insufficient oxygen levels (hypoxemia) in the blood, elevated carbon dioxide levels (hypercapnia), or both, causing critical impairment in organ function.
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
195
Acute Respiratory Failure-III01:30

Acute Respiratory Failure-III

Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
174