Related Experiment Video
Updated: Jun 23, 2025
06:03
Use of Viral Entry Assays and Molecular Docking Analysis for the Identification of Antiviral Candidates against Coxsackievirus A16
Published on: July 15, 2019
7.9K
Coxsackievirus A24 causing acute conjunctivitis in a 2023 outbreak in Vietnam
Huy Tran1, Thao Ha1, Linh Hoang1
1Hai Yen Vision Institute, Ho Chi Minh City, Vietnam.
Summary
Coxsackievirus A24v was the primary cause of the 2023 Vietnam conjunctivitis outbreak, with genetic links to a 2022 India outbreak. Ongoing surveillance is crucial for detecting viral co-circulation during such epidemics.
Area of Science:
- Ophthalmology
- Virology
- Epidemiology
Background:
- Conjunctivitis outbreaks pose a significant public health challenge.
- Identifying causative agents is crucial for effective control and prevention.
Purpose of the Study:
- To identify the specific pathogen responsible for the 2023 conjunctivitis outbreak in Vietnam.
- To understand the genetic relatedness of the circulating virus to previous outbreaks.
Main Methods:
- RNA sequencing was employed to detect and identify viral pathogens.
- Samples were collected from patients presenting with infectious conjunctivitis.
Main Results:
- Coxsackievirus A24v was identified as the predominant pathogen.
- Phylogenetic analysis revealed similarities between Vietnamese and Indian strains (2022 outbreak).
- Human adenovirus D was also detected; common symptoms included tearing, purulence, and itching.
Conclusions:
- Conjunctivitis outbreaks can involve the co-circulation of multiple viruses.
- Hemorrhagic conjunctivitis was not a prominent feature, despite association with Coxsackievirus.
- Continuous genetic surveillance, including RNA virus detection, is vital for timely outbreak detection.
More Related Videos
Related Concept Videos
01:30Acute Pharyngitis
576
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
576
00:57Viral Recombination
23.4K
Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
23.4K
01:23Chronic Pharyngitis
1.7K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
1.7K