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PD-1 Inhibitor Induced Hypertrophic Lichen Planus: A Case Report
Olivia Lim1, Eamonn Maher2, Daniel D Miller3
1MSIII Joan C. Edwards School of Medicine, Huntington, WV, USA. Lim19@marshall.edu.
Drugs in R&D
|June 14, 2024
Summary
This case highlights hypertrophic lichen planus mimicking squamous cell carcinoma in patients treated with PD-1 inhibitors. Early recognition and treatment of these lichenoid reactions are crucial for effective management.
Area of Science:
- Dermatology
- Oncology
- Immunology
Background:
- Programmed cell death protein 1 (PD-1) inhibitors are revolutionizing cancer treatment.
- Clinicians must be aware of diverse skin reactions to PD-1 inhibitors.
- Hypertrophic lichen planus (HLP) can mimic squamous cell carcinoma (SCC).

