Life Extension Should Come with Wisdom: Reflections and Questions for the Geroscience and Longevity Community

Area of Science:

• Geroscience
• Longevity Biotechnology
• Aging Research

Background:

• The field of geroscience has seen significant growth, with numerous organizations and a global movement focused on combating aging.
• This progress has led to calls for regulatory and policy changes and increased research funding.
• However, ethical, legal, and social implications (ELSI) have not kept pace with scientific advancements.

Purpose of the Study:

• To advocate for the integration of ethical and societal considerations into geroscience research and development.
• To propose key considerations for the longevity community to address potential societal impacts.
• To stimulate discussion on the responsible direction of aging research.

Main Methods:

• The article presents a critical analysis of the current state of geroscience.
• It outlines three essential considerations for the longevity community.
• It raises questions about the influence of external stakeholders on the field's trajectory.

Main Results:

• Progress in longevity biotechnology has outpaced ethical and societal discourse.
• There is a need for the geroscience community to engage with public attitudes and needs.
• Defining the primary goals (health span vs. lifespan) and the role of investors is crucial.

Conclusions:

• Geroscience must proactively address ethical, legal, and social implications to ensure responsible innovation.
• Understanding public perspectives and clarifying the field's objectives are vital steps.
• The influence of investors and major donors on research priorities requires careful examination to guide the future of human aging.