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A High-Throughput Luciferase Assay to Evaluate Proteolysis of the Single-Turnover Protease PCSK9
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VERVE-101, a CRISPR base-editing therapy designed to permanently inactivate hepatic PCSK9 and reduce LDL-cholesterol

Amanda J Hooper1,2, Xuan L Tang1, John R Burnett1,2

  • 1Department of Clinical Biochemistry, PathWest Laboratory Medicine WA, Royal Perth Hospital & Fiona Stanley Hospital Network, Perth, Western Australia, Australia.

Expert Opinion on Investigational Drugs
|June 15, 2024
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Base editingCRISPRLDLLDL-cholesterolPCSK9PCSK9 inhibitorVERVE-101VERVE-102

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