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MultiTrans: Multi-branch transformer network for medical image segmentation.

Yanhua Zhang1, Gabriella Balestra2, Ke Zhang3

  • 1Department of Electronics and Telecommunications, Politecnico di Torino, Corso Duca degli Abruzzi 24, Turin, 10129, Italy; School of Astronautics, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, 710072, China.

Computer Methods and Programs in Biomedicine
|June 15, 2024
PubMed
Summary
This summary is machine-generated.

This study introduces MultiTrans, an efficient Transformer architecture for medical image segmentation. It achieves superior accuracy by effectively processing high-resolution features and aggregating multi-scale global and local information.

Keywords:
Abdominal multi-organ segmentationCardiac segmentationDeep learningEfficient self-attentionMedical image segmentationMulti-branch transformers

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Area of Science:

  • Medical Image Analysis
  • Deep Learning
  • Computer Vision

Background:

  • Convolutional Neural Networks (CNNs) dominate medical image segmentation but struggle with global context.
  • Transformers offer global context but are computationally inefficient, often requiring downsampling or patch-based processing.
  • Patch-wise operations limit Transformers in capturing fine-grained, pixel-level details crucial for segmentation.

Purpose of the Study:

  • To develop a memory- and computation-efficient self-attention module for Transformers in medical image segmentation.
  • To design a novel Multi-Branch Transformer (MultiTrans) architecture capable of handling multi-scale features.
  • To improve the extraction of both global context and fine spatial details in medical images.

Main Methods:

  • Proposed an Efficient Self-Attention (ESA) module to enable reasoning on high-resolution features.
  • Introduced the Multi-Branch Transformer (MultiTrans) architecture with four parallel Transformer branches at different CNN levels.
  • Aggregated multi-scale global contexts and multi-scale local features through a hybrid CNN-Transformer approach.

Main Results:

  • MultiTrans achieved the highest segmentation accuracy across three diverse medical image datasets (Synapse, ACDC, M&Ms).
  • The proposed Efficient Self-Attention (ESA) significantly reduced training memory (18.77%) and computational complexity (20.68% FLOPs) compared to Standard Self-Attention (SSA).
  • ESA maintained or slightly improved segmentation accuracy while drastically reducing model parameters (74.07% reduction).

Conclusions:

  • The MultiTrans network demonstrates robust and generalizable performance on medical image segmentation tasks.
  • Ablation studies confirm the efficiency and effectiveness of the proposed Efficient Self-Attention (ESA) module.
  • The developed architecture addresses the limitations of existing methods, offering a more efficient and accurate solution for medical image segmentation.