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Is there an increased risk of otitis media in children with obstructive sleep apnea?
Chloe Cottone1, Eunice Im2, Sean Clausen3
1Jacobs School Medicine and Biomedical Sciences at the University at Buffalo, 955 Main St., Buffalo, NY, 14203, USA.
Insights
Children with Obstructive Sleep Apnea (OSA) have higher rates of otitis media and related surgeries. Conditions like allergic rhinitis may contribute to both OSA and ear infections in pediatric patients.
Area of Science:
- Otolaryngology
- Pediatric Sleep Medicine
- Epidemiology
Background:
- Obstructive Sleep Apnea (OSA) is a prevalent condition in children.
- The association between OSA and otolaryngologic disorders requires further investigation.
- Understanding these links can inform clinical practice and patient outcomes.
Purpose of the Study:
- To determine the prevalence of otitis media and related conditions in children with OSA.
- To compare these prevalences against a cohort of children without OSA.
- To identify potential contributing factors for observed differences.
Main Methods:
- A retrospective cohort study was conducted using the US Collaborative Network within TriNetX.
- Patients were categorized into OSA (ICD-10 G47.33) and non-OSA groups, with propensity score matching for age, sex, and race.
- Prevalence of otitis media, chronic otitis media, tympanostomy, adenoidectomy, tonsillectomy, adenotonsillectomy, and allergic rhinitis were compared.
Main Results:
- Children with OSA showed significantly higher likelihoods of otitis media (1.27x) and chronic otitis media (3.86x).
- Increased rates of tympanostomy (3.81x) and surgeries like adenoidectomy (4.1x), tonsillectomy (18.2x), and adenotonsillectomy (24.7x) were observed in the OSA group.
- Children with OSA were also more likely to have allergic rhinitis (2.03x).
Conclusions:
- Pediatric OSA is associated with a greater incidence of otitis media and subsequent surgical interventions.
- The increased prevalence of allergic rhinitis and adenoid hypertrophy in children with OSA may explain the higher frequency of acute otitis media (AOM).
- These findings highlight the interconnectedness of respiratory and ear conditions in children.
Introduction:
The purpose of this study was to investigate the prevalence of otitis media and other otolaryngologic disorders in children with Obstructive Sleep Apnea (OSA) compared to those without OSA in a large cohort.
Methods:
A retrospective cohort study was carried within the US Collaborative Network within TriNetX. The OSA group was defined by ICD-10 code G47.33 and non-OSA group excluded patients with OSA. Both groups were required to have a CPT code for an outpatient visit to act as a control: 99202-99215. Propensity score matching for age, sex, and race was performed. Prevalence of otitis media (ICD-10H65, H66), chronic otitis media (ICD-10H66.1, H66.2, H66.3, H65.2, H65.3, and H65.4), tympanostomy (CPT 69433, 69436), adenoidectomy (CPT 42830, 42831), tonsillectomy (CPT 42825, 42826), adenotonsillectomy (CPT 42820, 42821), and allergic rhinitis (ICD-10 J30.9) were compared in this cohort.
Results:
Propensity score matching yielded 165,665 (M = 95949, F = 69901) patients with a mean age of 10.7 (SD = 4.07) for each cohort. Children with OSA were 1.27x and 3.86x more likely to be diagnosed with otitis media and chronic otitis media, respectively (P<.0001). They were 3.81x more likely to undergo a tympanostomy (P<.0001). Children with OSA were 4.1x, 18.2x, and 24.7x more likely undergo an adenoidectomy, tonsillectomy, and adenotonsillectomy, respectively (P<.0001). Children with OSA were also 2.03x as likely to have a diagnosis of allergic rhinitis (P<.0001).
Conclusion:
Children with OSA experience otitis media and related surgical intervention more than children without OSA. Since allergic rhinitis and adenoid hypertrophy are contributors to both OSA and AOM, their increased prevalence in children with OSA may explain their increased frequency of AOM.
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