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Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images
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Cerebral microbleeds is a predictor of recurrent small vessel cerebrovascular disease: Evaluation based on the

Satoshi Hori1, Soshi Okamoto2, Michiya Kubo2

  • 1Department of Neurosurgery, Stroke Center, Saiseikai Toyama Hospital, Toyama, Japan; Department of Neurosurgery, Graduate School of Medicine and Pharmaceutical Science, University of Toyama, Toyama, Japan.

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
|June 15, 2024
PubMed
Abstract

Insights

The number of cerebral microbleeds (CMBs) predicts recurrent strokes like lacunar infarction and intracerebral hemorrhage. An increase in CMBs strongly correlates with the deep lacunar infarction/non-lobar ICH recurrence pattern.

Area of Science:

  • Neurology
  • Vascular Neurology
  • Neuroimaging

Background:

  • Cerebral microbleeds (CMBs) are linked to recurrent small vessel cerebrovascular diseases.
  • The specific recurrent stroke patterns associated with CMBs remain unclear.

Purpose of the Study:

  • To investigate the association between the number of CMBs and recurrent stroke patterns.
  • To determine if CMB dynamics differ based on recurrent stroke types.

Main Methods:

  • 217 patients with first stroke (lacunar infarction or non-lobar ICH) were analyzed.
  • Baseline and new CMBs were compared between recurrent and non-recurrent stroke groups.
  • CMB dynamics were evaluated across different recurrent stroke patterns.

Main Results:

  • Higher baseline and newly appearing CMBs were significantly associated with recurrent stroke.
  • The deep lacunar infarction/non-lobar ICH recurrence pattern showed significantly more newly appearing CMBs.
  • CMB counts varied significantly depending on the specific recurrent stroke pattern.

Conclusions:

  • CMB burden is associated with recurrent lacunar infarction and non-lobar ICH.
  • The increase in CMBs is particularly indicative of the deep lacunar infarction/non-lobar ICH recurrence pattern.
Keywords:
Cerebral microbleedsIntracerebral hemorrhageLacunar infarctionRecurrent strokeSmall vessel cerebrovascular diseaseT2*-weighted MRI

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