Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Radiation: Applications

Radiation: Applications

The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
The average...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Proton FLASH preserves neurocognition across delivery techniques: implications for clinical translation in pediatric brain tumors.

bioRxiv : the preprint server for biology·2026

Same author

Hybrid Curriculum Learning for Data-Efficient Lung Nodule Detection with YOLOv11.

Diagnostics (Basel, Switzerland)·2026

Same author

Neoadjuvant Chemotherapy and Stereotactic Body Radiation Therapy in Patients with Early-Onset Pancreatic Cancer: Clinical Outcomes and Toxicity.

Cancers·2026

Same author

Evaluating Curvature-Induced Variation in Deep Learning-Based Beamforming for Flexible Transducers in Ultrasound-Guided Radiation Therapy.

Bioengineering (Basel, Switzerland)·2026

Same author

Sacral Fractures After Short-Course Radiation Therapy for Rectal Cancer.

Advances in radiation oncology·2026

Same author

The combination of a cancer vaccine, pembrolizumab, and stereotactic body radiation in patients with locally advanced pancreatic cancer: a single-arm, phase II study.

Nature communications·2026

Search research articles

Related Experiment Video

Updated: May 11, 2026

Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy

Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy

Published on: October 18, 2011

Democratizing FLASH Radiotherapy.

Michele Moreau¹, Serena Mao², Uriel Ngwa³

¹Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Hospital, Baltimore, MD..

Seminars in Radiation Oncology

|June 16, 2024

Summary

FLASH radiotherapy (RT) offers ultra-high dose rates to reduce healthy tissue damage. Democratizing this advanced cancer treatment requires technological validation, mechanistic understanding, and optimized delivery for global accessibility.

More Related Videos

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

Author Spotlight: Improving Radiation Therapy Access with Radiation Planning Assistant

Author Spotlight: Improving Radiation Therapy Access with Radiation Planning Assistant

Published on: October 6, 2023

Related Experiment Videos

Last Updated: May 11, 2026

Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy

Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy

Published on: October 18, 2011

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

Author Spotlight: Improving Radiation Therapy Access with Radiation Planning Assistant

Author Spotlight: Improving Radiation Therapy Access with Radiation Planning Assistant

Published on: October 6, 2023

Area of Science:

Oncology
Radiation Oncology
Medical Physics

Background:

FLASH radiotherapy (RT) utilizes ultra-high dose rates (>40 Gy/s) for cancer treatment.
This technique shows potential for reduced damage to healthy tissues compared to conventional RT.
Global accessibility and affordability of FLASH RT are critical for its widespread impact.

Purpose of the Study:

To review recent developments in FLASH RT technology and its applications.
To discuss strategies for democratizing FLASH RT worldwide.
To explore the potential of FLASH RT in combination with immunotherapy.

Main Methods:

Review of current literature on FLASH RT advancements.
Analysis of technological requirements for accurate dose delivery and measurement.
Examination of mechanistic understanding and optimization of FLASH RT parameters.
Exploration of FLASH radioimmunotherapy and nanomedicine applications.

Main Results:

FLASH RT has the potential to revolutionize cancer treatment by sparing healthy tissues.
Technological upgrades, mechanistic insights, and optimized parameters are key to advancing FLASH RT.
FLASH RT may enhance tumor immunogenicity, paving the way for novel radioimmunotherapies.

Conclusions:

Democratizing FLASH RT necessitates cross-disciplinary collaboration for technological, mechanistic, and clinical advancements.
Optimizing dose rate, fractionation, and beam quality is crucial for efficacy across different tumor types.
Combining FLASH RT with immunotherapy holds significant promise for improved cancer treatment outcomes globally.