Evolution of Metabolic Syndrome in Newly Diagnosed Type 2 Diabetes Mellitus Asian-Indian Patients Over the Last 15 Years using Adult Treatment Panel III of the National Cholesterol Education Program, World Health Organization, and International Diabetes Federation Criterion
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Summary
This summary is machine-generated.Metabolic syndrome (MetS) incidence is high in Asian-Indian patients with type 2 diabetes (T2D), increasing from 2004-2019. Central obesity and dyslipidemia were more common in women, while hypertension was more prevalent in men.
Area Of Science
- Endocrinology and Metabolism
- Diabetes Mellitus Research
- Cardiovascular Risk Factors
Background
- Metabolic syndrome (MetS) is a cluster of conditions that increases the risk of heart disease, stroke, and type 2 diabetes (T2D).
- Understanding the trends in MetS incidence among diverse populations is crucial for public health initiatives and clinical management.
Purpose Of The Study
- To assess the changing trends in MetS incidence in Asian-Indian patients newly diagnosed with T2D.
- To evaluate MetS and its components using NCEP-ATP III, WHO, and IDF criteria.
- To examine gender-wise patterns of MetS incidence and its components over time.
Main Methods
- Retrospective observational study of 10,950 newly diagnosed T2D patients from 2004-2019.
- MetS incidence assessed using NCEP-ATP III, WHO, and IDF criteria across three time periods (2004-2008, 2009-2013, 2014-2019).
- Statistical analysis included Chi-square tests and ANOVA to compare incidence and gender-wise patterns.
Main Results
- Overall MetS incidence was 80.9% (NCEP-ATP III), 65.4% (WHO), and 69.8% (IDF).
- A steady increase in MetS incidence was observed from 2004 to 2019.
- Central obesity, hypertension, and dyslipidemia were the most prevalent components, with increasing trends over time. Women showed higher central obesity and dyslipidemia; men had higher hypertension.
Conclusions
- MetS is highly prevalent in Asian-Indian patients with newly diagnosed T2D, with a significant increasing trend observed.
- NCEP-ATP III criteria identified a higher incidence of MetS compared to WHO and IDF criteria.
- Targeted lifestyle interventions and pharmacological management are recommended to mitigate MetS risks.
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