REM sleep behavior disorder in Brunner syndrome
Eduard Cesari1, Amaia Muñoz-Lopetegi2,3, Joan Santamaria2,3
1Department of Psychiatry, Hospital Clínic de Barcelona, Barcelona, Spain.
Summary
Brunner syndrome, a genetic disorder, can manifest as REM sleep behavior disorder. This condition involves acting out dreams, potentially due to increased monoaminergic activity in affected individuals.
Area of Science:
- Neurogenetics
- Sleep Medicine
- Psychiatry
Background:
- Brunner syndrome is an X-linked disorder linked to MAOA deficiency, causing intellectual disability and aggression.
- Increased monoaminergic activity is a hallmark of Brunner syndrome.
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