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A multimodal MRI study of XNKQ acupuncture for limb dysfunction after ischemic stroke: a randomized controlled study
Chunlei Tian1,2, Lingyong Xiao1,2, Ruiyu Li1,2
1Department of Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Frontiers in Neurology
|June 17, 2024
Summary
This study investigates Xingnao Kaiqiao (XNKQ) acupuncture's effects on limb motor dysfunction after cerebral ischemic stroke (CIS) using multimodal MRI. Findings will support XNKQ acupuncture in stroke rehabilitation.
Area of Science:
- Neuroscience
- Rehabilitation Medicine
- Medical Imaging
Background:
- Limb motor dysfunction is a significant challenge post-cerebral ischemic stroke (CIS), impacting patient quality of life.
- Multimodal magnetic resonance imaging (MRI) offers insights into central nervous system mechanisms.
- Xingnao Kaiqiao (XNKQ) acupuncture is a potential therapeutic intervention for stroke recovery.
Purpose of the Study:
- To investigate the central mechanisms underlying the curative effects of Xingnao Kaiqiao (XNKQ) acupuncture in patients with cerebral ischemic stroke (CIS).
- To provide evidence supporting the application of XNKQ acupuncture in stroke rehabilitation.
- To utilize multimodal MRI as a primary outcome measure for assessing treatment efficacy.
Main Methods:
- A randomized controlled trial design comparing XNKQ acupuncture plus conventional treatment versus conventional treatment alone.
- Recruitment of patients meeting specific criteria and random allocation into treatment or control groups.
- Inclusion of a healthy control group and a 14-day treatment course, with multimodal MRI analysis and adverse event monitoring.
Main Results:
- Primary outcome will be assessed through multimodal MRI analysis.
- Safety will be evaluated by observing and recording adverse events.
- Detailed results are pending publication in a peer-reviewed journal.
Conclusions:
- The study aims to elucidate the neuroimaging basis of XNKQ acupuncture's efficacy in CIS.
- Results are expected to strengthen the evidence base for XNKQ acupuncture in stroke rehabilitation.
- The findings will contribute to understanding advanced neuroimaging applications in stroke recovery.
