Related Experiment Video
Updated: Jun 23, 2025

07:32
Author Spotlight: 3D Movement Assessment of Maxillary Posterior Teeth in Clear Aligner Treatment
Published on: February 23, 2024
1.1K
Accelerated Orthodontic Treatment using Biomodulation: A Randomized Clinical Trial
Marie A Ambroise1, Tara V Avirachan2, S Brijesh3
1Department of Orthodontics, Sri Venkateswara Dental College, Puducherry, India.
Journal of Pharmacy & Bioallied Sciences
|June 17, 2024
Summary
Low-level laser therapy (LLLT) significantly speeds up orthodontic treatment, reducing overall duration by 30%. This biomodulation technique also decreases pain perception and accelerates tooth movement during orthodontic therapy.
Area of Science:
- Orthodontics
- Biomedical Engineering
- Laser Therapy
Background:
- Orthodontic treatment can be lengthy and burdensome for patients.
- Biomodulation techniques offer potential solutions to accelerate tooth movement.
Purpose of the Study:
- To evaluate the efficacy of low-level laser therapy (LLLT) as a biomodulation technique to expedite orthodontic tooth movement.
- To assess the impact of LLLT on treatment duration, pain perception, and the rate of tooth movement in orthodontic patients.
Main Methods:
- A randomized clinical trial involving 60 orthodontic patients (aged 12-30) was conducted.
- Patients were divided into two groups: a biomodulation group receiving LLLT with fixed appliances and a control group receiving conventional treatment.
- Treatment duration, pain, and tooth movement were assessed throughout the study.
Main Results:
- The biomodulation group showed a 30% reduction in overall treatment time (8.4 months vs. 12 months, P < 0.001).
- Patients in the biomodulation group reported lower pain perception.
- A statistically significant increase in the rate of tooth movement was observed, with a 20% reduction in time to achieve alignment (P < 0.01).
Conclusions:
- Biomodulation using LLLT is a promising adjunct to conventional orthodontic treatment.
- LLLT significantly accelerates orthodontic tooth movement and reduces overall treatment duration.
- LLLT may improve patient comfort during orthodontic therapy.

