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Sirolimus Use in Refractory Crohn's Disease

Rex K Siu1, Christian Karime1, Jana G Hashash2

  • 1Department of Internal Medicine, Mayo Clinic Florida, Jacksonville, FL.

ACG Case Reports Journal
|June 17, 2024
PubMed
Summary

Sirolimus shows potential benefits for refractory Crohn's disease (CD) in adults, but adverse effects frequently lead to treatment discontinuation. Further research is needed to optimize its use in managing this chronic inflammatory condition.

Keywords:
Crohn's diseaseadverse effectsextremity edemaimmunomodulatorinflammatory bowel diseasepoor wound healingsirolimus

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